4th Educational Workshop on Immunoglobulin

Sequence Analysis in CLL

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Welcome

CLL ontogeny: options and possibilities

Mechanisms of immunoglobulin diversity

Clinical relevance of IG gene sequence analysis in CLL

(Handouts)

From the patient to the sequence: Primers, PCR, Detection of clonality, Sequencing

How to analyze IG sequences: the IMGT/V-QUEST tool 

Basic Exercises I

Basic Exercises II

Navigation through the IMGT web- resources

Introduction to 'trouble' cases

Exercises

ERIC recommendations/Review Board

How to report IG sequence data in clinical routine? 

Cases difficult to categorize - how to handle them?

Stereotyped BcR in CLL 

(References)

Data handling and analysis: standards before innovation 

Turning integration of data and expertise into innovation 

Concluding remarks  

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