Thursday 9 October 2008

9.00

Welcome

Frederic Davi

 

Session I - IG genes in CLL: biological and clinical aspects

Chair:

Richard Rosenquist

9.10

Mechanisms of Immunoglobulin diversity

Frederic Davi

9.40

Keynote Lecture

Clues to the immunopathogenesis of B-cell malig-nancies from the analysis of the clonotypic BCR

Freda Stevenson

10.20

Somatic hypermutation as a prognostic marker in CLL - relationship to other prognostic markers

Paolo Ghia

10.50

Coffee

 

Session II - IG genes in CLL: technical aspects

Chair:

Kostas Stamatopoulos

11.20

From the patient to the sequence: Primers, PCR, clonality and sequencing

Anton Langerak

11.50

ERIC recommendations on IG gene analysis in CLL Richard Rosenquist

12.10

On-line tools for interpretation of IG sequences

Marie-Paule Lefranc

12.40

Lunch

 

Session III - Interpretation of IG sequences and database searches (tutorial)

13.45

How to use the IMGT/V-QUEST tool

Véronique Giudicelli

14.00

Basic Exercises I

15.30

Solutions

Kathleen Potter

16.00

Coffee

16.30

Navigation through the IMGT web resources

Marie-Paule Lefranc

17.00

Basic Exercises II

18.30

Solutions

Kathleen Potter

19.00

Cocktail reception

 

Friday 10 October 2008

 

Session IV - Interpretation of trouble sequences (tutorial)

9.00

Introduction to ‘trouble sequences’

Chrysoula Belessi

9.30

Exercises

11.30

Solutions

Chrysoula Belessi

12.30

Lunch

 

Session V - Ig gene analysis in clinical routine

Chair:

Paolo Ghia

13.30

How to report IG gene data in clinical routine?

Cases difficult to categorize – how to handle them?

Richard Rosenquist

14.00

ERIC review board: an online support for troubleshooting

Anton Langerak

Session VI - IG genes in CLL: Beyond Somatic Hypermutation

Chair:

Frederic Davi

14.30

Stereotyped B-cell Receptors in CLL

Kostas Stamatopoulos

15.00

A new perspective on large scale bioinformatics and IG gene analysis in CLL

Nikos Darzentas

15.30

Conclusion/perspective

Florence Cymbalista

16.00

Meeting adjourns

 

Download program (Microsoft Word format)