Program

 

4th Educational Workshop on Immunoglobulin Sequence Analysis

in Chronic Lymphocytic Leukemia

Stresa, 6-7 April 2011

 

 

Hotel La Palma

Lungo Lago Umberto I, 33

Stresa, ITALY

http://www.hlapalma.it

 

 

Program

 

Wednesday 6 April 2011

 

9.00        Welcome                                                                                          P. Ghia

 

9.10        Key-note lecture

               CLL ontogeny: options and possibilities                                       M. Ferrarini

 

 

Session I - IG sequences in CLL: biological and clinical aspects

 

Chair:      Paolo Ghia

 

10.00      Mechanisms of immunoglobulin diversity                                      F. Davi

 

10.30      Clinical relevance of IG gene sequence                                         R. Rosenquist

               analysis in CLL (Handouts)

 

11.00      Coffee break

 

 

Session II - IG sequences in CLL: technical aspects

 

Chair:      Frederic Davi

 

11.30      From the patient to the sequence:                                                  A. Langerak

               Primers, PCR, Detection of clonality, Sequencing

 

12.30      How to analyze IG sequences: the IMGT/V-QUEST tool                 V. Giudicelli

 

13.00      Lunch

 

 

Session III - Interpretation of IG sequences: bioinformatics

 

Chair:      Anton Langerak

 

14.15      Basic Exercises I

 

15.10      Solutions                                                                                           F. Murray

 

15.30      Basic Exercises II

 

16.30      Coffee break

 

16.45      Solutions                                                                                           K. Potter

 

17.15      Navigation through the IMGT web- resources                      M-P Lefranc

 

19.00      Boat departure

 

19.15      Aperitif at Isola Pescatori

 

20.00      Dinner at Isola Bella

 

Thursday 7 April 2011

 

Session IV - Interpretation of IG sequences: 'trouble' cases

 

Chair:      Marie-Paule Lefranc

 

8.30        Introduction to 'trouble' cases                                                        C. Belessi

 

9.00        Exercises

 

10.0     Solutions                                                                                          C. Belessi

 

10.30      Coffee break

 

 

Session V - IG sequence analysis in clinical routine

 

Chair:      Paolo Ghia

 

11.00      ERIC recommendations/Review Board                                           F. Davi

 

11.30      How to report IG sequence data in clinical routine?                      R. Rosenquist

               Cases difficult to categorize - how to handle them?

 

 

Session VI - Enabling innovative IG sequence research in CLL: present and future

 

Chair:      Richard Rosenquist

 

12.00      Stereotyped BcR in CLL (References)                                             K. Stamatopoulos

 

12.20      Data handling and analysis: standards before innovation             A. Hadzidimitriou

             

12.40      Turning integration of data and expertise into innovation             N. Darzentas

 

 

13.00      Concluding remarks                                                                         P. Ghia

 

13.05      Lunch

 

Download program here